Role of Serotonin Hormone at Development of Diabetes Mellitus Type 2 disease

Subject :Diabetes Mellitus (DM) type 2 is most common disease characterized by elevation of serum glucose level due to impair insulin production or impair cell response to insulin .Serotonin is hormonal neurotransmitter commonly found in brain cell but it also present in beta cells of pancreas . It is key hormone that stabilizes mood, feelings of well-being, and happiness . Objective of the Study: Role of serotonin in development of DM type 2 disease . Materials and Methods: This study was done on 30 patients with un-control DM type2 patients and 30 control DM type 2 patients , the all subjects age within this study were more than 50 years of both genders .After obtained serum , immediately used quantity method for measured level of serum serotonin concentration . Results: This study shows reduce of serum serotonin concentration level in un-control DM type 2 group compare with control group . Conclusion: This study confirms that decreased serum serotonin concentration level can act as support development of DM type 2 disease .